Chiropractic theory holds that many diseases, asthma included, may stem from spinal subluxations that impinge upon the bodies flow of energy.  By permitting the nervous system to function with less stress, it is believed that the immune system is then permitted to function more efficiently. According to some chiropractors, adjustments free up the nervous system so that the nerves are no longer irritated and hypersensitive to immune stimuli.

In spite of this theory, randomized controlled studies are unable to present conclusive data on adjustments being beneficial for allergy symptoms.

According to the results of Takeda et al. in March of 2003 there may be a possibility that  chronic nerve compression secondary to vertebral subluxation in the thoracic and lumbar regions contributes significantly to an individual's allergy symptoms. It is postulated that the compression results in poor neuronal conductance and thus "leads to a chronic functional disorder having a significant effect on digestion, absorption of nutrients and liquids, conveyance of food as well as various other functions of the digestive tract extending to excretion."