Acute Mountain Sickness

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Definition

Acute Mountain sickness (AMS) is a syndrome that affects individuals who ascend above 2000m.  This reversible condition results from failed physiological adaptation to acute hypobaric hypoxia.

Symptoms

Symptoms of mild to moderate AMS include

  • Headache
  • Difficulty sleeping
  • Loss of appetite
  • Nausea or vomiting
  • Fatigue
  • Dizziness or light-headedness
  • Tachycardia
  • Shortness of breath

 Symptoms of severe AMS include

  • Cough
  • Shortness of breath at rest
  • Chest tightness or congestion
  • Cyanosis
  • Hemoptysis
  • Inability to walk in a straight line
  • Decreased consciousness
  • Confusion
  • Cerebral edema

Complications

Complications of AMS include pulmonary edema, coma, and high altitude cerebral edema.

Traditional treatment

Treatment includes the following:

  • Prevention
    • Gradual ascent
      • Stop for 1-2 days of rest for each 2000 feet above 8000 feet
    • Oxygen supplementation above 9840 feet
    • Acetazolamide (Diamox) 1 day before ascent, and 1-2 days into
    • Drinks lots of fluids, avoid alcohol and caffeine, and eat regularly
  • Descend to a lower altitude as fast and safe as possible (Gold standard)
  • Administration of oxygen

 

For cerebral edema, treatment consists of dexamethasone.

For pulmonary edema, treatment includes oxygen, nifedipine, and in severe cases, mechanical ventilation.

Herbal treatment

Several studies have been conducted to determine the effectiveness of ginkgo in treating AMS, including:

  • The 1996 French Study
  • The 2000 Pike Peak's Study
  • The 2002 Hawaii Study
  • The 2004 PHAIT Study
  • The 2005 Ginkgo vs. Acetazolamide Study

The research shows that Ginkgo is effective in treating AMS, but when compared to Acetazolamide, it is not as effective.