• Mild gastrointestinal upset
• Headache
• Dizziness
• Palpitations
• Constipation
• Allergic skin reactions

Large doses

• Restlessness

• Diarrhea

• Nausea

• Vomiting

• Lack of muscle tone

• Weakness

• Excessive spontaneous bleeding, such as subdural hematoma, subarachnoid or parietal hemorrhage, and spontaneous hyphema (rare)

Drug Interactions

Anticoagulant or antiplatelet drugs 

• Increased bleeding risk

Insulin

• Secretion and metabolism affected, altering blood glucose levels

Thiazide diuretics

• Increased blood pressure

Trazodone

• Association with a coma by either acting on the benzodiazepine receptors with a GABA-ergic activity, or increasing the metabolism of trazodone to active GABA-ergic metabolites

Contraindications

• Hypersensitivity to any ginkgo preparation
• Children
• Pregnant women
• Patients with known risk factors for intracranial hemorrhage